Program

Thursday, nov 16th

9-12:   SFBMEc Avenir

13:00 : Welcome participant

13:15 : Introduction - Welcome from the President of SFBMEc

13:30 - 14:30 : Session I “Role of ECM in cancer development” – sponsored by Apmonia Therapeutics 

13:30 -14:00 : Stéphane Dedieu (CNRS - MEDyC, Reims) : The LRP1 as a sensor of the ECM: implications for tumour biology and clinical perspectives

Short communications : 

14:00 - 14:15 : Célia Thomas (IRSET, Rennes) : Association of Fibulin-3 with liver fibrosis, a new regulator of hepatic stellate cell homeostasis?

14:15 - 14:30 : Lambert Ambroise (MEC-uP, CY Cergy Paris Université) : Flash multiscale tuning of cell-microenvironment interactions in Ovarian cancer

Sponsor communications : 

14:30 - 14:40 : Apmonia Therapeutics

14:40 - 14:50 : Leica Microsystemes

14:50 - 15:00 : Eden Instruments

15:00 : Coffee break and poster session

16:30 - 17:00 : Sophie Tartare-Deckert (INSERM - C3M, Nice) : The role of ExtraCellular Matrix in melanoma cell plasticity and resistance to targeted therapy

Short communications :

17:00 - 17:15 : Fabien Foucher (NuMeCan, Rennes) : Raman spectra are associated with the matrisome of intratumor fibrosis in human hepatocellular carcinoma

17:15 - 17:30 : Vivien Paturel (UMR 7369, Reims) : Development of a peptide targeting tumor angiogenesis in colorectal cancer and study of intercellular communication via extracellular vesicles

17:30 - 17:45 : Hasna Maayouf (UMR 7361, IS2M, Mulhouse) : Virus-Like Particle as a signaling platform to mimic cell-matrix interactions at the nanoscale for the control of cell behavior

18:00 : departure for social event : "Visit of the historic wine cellar of Strasbourg Hospices"

19:45: Diner  “Au cerf d’or“ - On pre-registration

Friday, nov 17^th

8:30 :  Session II “Physiopathological functions of the ECM”

8:30 - 9:00 : Eva Faurobert (CNRS - IAB, Grenoble) : Mechanical modulation of intercellular communication via the remodelling of the extracellular matrix in endothelial pathological contexts

Short communications :

9:00 - 9:15 : Hisoilat Bacar (IGFL, Lyon) : Zebrafish as an emerging model for studying the dynamics of skin regeneration

9:15 - 9:30 : Fabien Lecaille (CEPR, Tours) : The potential beneficial effects of neohesperidin dihydrochalcone on cathepsin S in reconstructed human skin

9:30 - 9:45: Manon Napoli (LBTI, Lyon) : Role of PCPE-2 (procollagen C-proteinase enhancer-2) in skin homeostasis and wound healing

10:00 : Coffee break and poster session

11:00 - 11:30: Patricia Albanese – (CNRS –Gly-CRRET, Paris-Créteil) : Role of heparan sulfate sulfation in the pathophysiology of the osteoarthritic joint 

Short communications :

11:30 -11:45 : Laurie Nemoz-Billet (ENS, Lyon) : Dual topologies of myotomal collagen XV and tenascin C act in concert to guide and shape developing motor axons

11:45 -12:00 : Zakaria Mougin (LVTS INSERM U1148, Paris) : The Critical Role of the TB5 domain of Fibrillin-1 in Endochondral Ossification

12:00 : General assembly of the SFBMEc

13:00 : Lunch and poster session

14:30 - 16:00 : Session III “ECM assembly and dynamics”

14:30 - 15:00 : Viola Vogel (ETH Zurich, Suisse) : Platelets drive fibronectin fibrillogenesis using integrin αIIbβ3

Short communications :

15:00 - 15:15 : Catherine Moali (LBTI, Lyon) : The dark side of procollagen C-proteinase enhancer-2 (PCPE-2): inhibition of bone morphogenetic protein-1/tolloid-like proteinases

15:15 - 15:30 : Jean-Baptiste Vincourt (IMoPA, Vandoeuvre-lès-Nancy) : Collagen exhibits tissue-specific positional profiles of prolyl-4-hydroxylation determined by expression levels of P4HA isoenzymes

15:30 - 15:45 : Julia Huguet Herrero (LVTS INSERM U1148, Paris) : Role of ADAMTSL6 in progressive TAA formation

15:45 - 16:00 : Claire Masson (UMR_S1255, Strasbourg) : β1 and β3 integrins control the extracellular matrix surrounding megakaryocytes and their attachment to the vascular niche

16:15 : Awards ceremony and closing remarks